End of training? Scientists develop medicine that replicates the effects of exercise on the body

In a scenario in which health and well-being are increasingly in focus, medical science continues to surprise with innovations that could revolutionize the way we approach issues such as weight control and physical activity.

Recently, a new medication was revealed as a promising alternative for those looking for an effective way to reduce body weight. This remedy mimics the beneficial effects of physical activity, offering the possibility of a more accessible and practical approach to weight loss.

Understand how the medicine that simulates the effects of physical activity works

Photo: jcomp/Freepik

The new drug, classified as an exercise mimetic, is in the initial phase of development and should offer benefits similar to those of physical activity. Although it is still in the research phase, the substance could be a promising approach to treating conditions such as diabetes, obesity and age-related muscle loss.

The drug SLU-PP-332 does not influence appetite or exercise, but it stimulates a metabolic pathway that mimics the effects of physical training, increasing energy expenditure and accelerating fat metabolism in the body.

“This compound is essentially instructing skeletal muscle to make the same changes seen during resistance training. When we treat rats with this drug, we can see that their entire metabolism is focused on using fatty acids, which is very similar to what happens in people who are fasting or exercising. And the animals start to lose weight”, explains Thomas Burris, a professor at the University of Florida who led research into the medicine.

The new drug, targeting ERR proteins responsible for metabolic pathways in high-energy-consuming tissues such as muscles, heart and brain, resulted in an average weight loss of 12% in obese rats, without affecting food intake. foods or increase exercise.

Furthermore, there is evidence that the compound may be effective in treating heart failure by strengthening the heart muscle. To date, no serious side effects have been observed. Scientists plan to advance research to turn the drug into a pill and conduct additional testing before considering human trials.

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